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When you run into this problem, you can delete or move the mysql.sock file.
In this instance, we just removed the file:
rm -rf /var/lib/mysql/mysql.sock
In this instance, we just moved it to a .bak file.
mv var/lib/mysql/mysql.sock /var/lib/mysql/mysql.bak
service mysqld restart
Restarting the service creates a new entry called mqsql.sock